Programme

10:20 AM–12:40 PM

Lecture Session I – Epidemiology, Evolution, and Classification
(Chair: Raul Andino)

1. Nick Knowles: Taxonomy of the Picornaviridae: Update 2026
2. Nadia Neuner-Jehle: Reproducible Clade Nomenclature For Non-Polio Enteroviruses With Nextclade
3. Alex Shaw: A Global Pilot of Direct Molecular Detection and Nanopore Sequencing of Poliovirus for Stool Surveillance
4. Yemisi Adedeji: Optimising Environmental Surveillance Methods for Poliovirus Detection Using Direct Detection and Nanopore Sequencing
5. Lauren McCormick: The Role of Recombination in the Differential Diversification of Structural and Nonstructural Proteins across Human Enteroviruses
6. Beatriz Álvarez-Rodríguez: Comparative Analysis of Deep Mutational Scanning Datasets in Enteroviruses A and B Identies Functional Divergence and Therapeutic Targets
7. Corentin Aubé: Phylogenetic Analysis of Enteroviruses From Non-Human Primates Reveals Two New Species Within the Genus Enterovirus and Inter-Species Recombination

Lecture Session II – Virus Structure and Entry
(Chair: Yury Bochkov)

1. Frank van Kuppeveld: Live Imaging of Cytosol-Accessible dsRNA Illuminates the Dynamics of dsRNA Formation and Shielding During Picornavirus Infection
2. Han Kang Tee: Tunneling Nanotubes: An Alternative Route of Enterovirus A71 for Cell-To-Cell Infection
3. Natalie Kingston: Enterovirus VP0 Is an Autocatalytic Acid Protease
4. Ashley Pereirinha da Silva: Sialic Acid-Containing Glycolipids Extend the Receptor Repertoire of Enterovirus-D68
5. Bob Coelingh: Identification and Ultrastructure of Enterovirus Replication Organelles by in Situ cryo-ET
6. Harry McFarlane: Structural Investigation of Cardiovirus Rueckerti Receptor Interactions
7. Liya Mukhamedova: Echovirus 18 Uncoating In Vivo

Lecture Session II – Virus Structure and Entry
(Chair: Shin-Ru Shih)

1. Miguel Aracena Velazquez: Structural and Mechanistic Insights Into Translation Initiation on the Enterovirus Type 1 IRES
2. Alesia Levanova: A Structural Approach to Developing VLP Based Vaccines and Antiviral Agents Against Group B Coxsackieviruses
3. Giann Kerwin Dellosa: Microsecond Time-Resolved and Conventional cryo-EM Reveal Early Intermediates to Acid-Induced Capsid Dissociation of Foot-And-Mouth Disease Virus
4. Victor Pisabarro Montoro: Structure-Guided Engineering of 2C-Tagged CVB3 to Dissect Replication Organelle Formation in Time and Space
5. Tim Skern: Modelling the Structure of Poliovirus 2Apro
6. Walker Orr: Fitness Tradeoffs and Functional Hotspots in the Enterovirus A71 Capsid

Lecture Session III – Translation, Replication, and Virus Transmission
(Chair: Urs Greber)

1. Alessandro Savi: The Importance of Timing: How Translation and Replication Dynamics Shape Coinfection, Superinfection and Recombination of Rhinoviruses
2. Camille Duflos: Impact of the Phosphorylation of Viral Polymerases on Viral Replication
3. Sponsor's Talk: SPECION, s.r.o.

Lecture Session III – Translation, Replication, and Virus Transmission
(Chair: Shubhada Bopegamage)

1. Ron Geller: The Enterovirus Polymerase Drives Adaptation to Altered Temperature Conditions
2. Typhaine Filhol: Genome-Wide CRISPR Screen Identifies SEC63 as a Proviral Factor for EV-D111 Replication
3. Matthew James: Two Cellular AAA+ ATPases, RUVBL1 and RUVBL2, Associate With Rhinovirus Non-Structural Protein 2C and Are Essential for Viral RNA Replication
4. Valeria Lulla: Translation Initiation in Enterovirus Genomes
5. Sofie Midgley: Circulation of Coxsackieviruses in Denmark, 2006-2025
6. Eric Poeschla: Parabiosis and Marrow Transplantation Differentially Transfer Innate Immune System Properties of Picornaviral RdRp Transgenic Mice

Lecture Session IV – Virus-Host Interactions and Immune System
(Chair: Lars-Anders Carlson)

1. Daniel Moss: Mechanisms of Antibody-Mediated Neutralization of EV-D68
2. Aleksandar Antanasijevic: Electron Microscopy Mapping of Anti-Enterovirus Antibodies in IVIG Formulations
3. James Kelly: Mechanisms of Host Adaptation: The Interplay Between Viral 2A Proteases and Translation Initiation Factor eIF4G
4. Joep Korsten: An Advanced Human Intestinal Model for Studying Picornavirus Host-Pathogen Interactions, Antiviral Therapies, and Multiorgan Dynamics
5. David Aponte-Diaz: A Cytoplasmic Role for FOS in Driving Lipid Flux During Picornavirus Multiplication

Lecture Session IV – Virus-Host Interactions and Immune System
(Chair: Esther Nolte-'t Hoen)

1. Takayuki Abe: Parechovirus 3C Protease Interferes MDA5-Mediated Type-I IFN Expression in Culture Cells
2. Mariana Marques: Foot-And-Mouth Disease Virus Proteases Manipulate G3BP1 Activity Independently of Stress Granules Formation
3. Lisa Bauer: Non-Polio Enteroviruses Compromise the Electrophysiology of a Human iPSC-Derived Neural Network
4. Yousuf Anwar Khan: Functional and biochemical studies of 2C, a AAA+ complex
   
5. Thomas Michiels: The Leader (L) Protein of Cardioviruses: Using Convergent Short Linear Motifs (SLIMs) to Interfere With IFN Gene Induction and PKR Activation

Lecture Session V – Pathogenesis, Prevention, and Treatment
(Chair: Valeria Lulla)

1. Heikki Hyoty: Enterovirus Infections Are Associated With the Initiation of Autoimmunity That Links to Type 1 Diabetes – Prospective TEDDY Study
2. Amina Yasmin: Development of in Vitro Tests for FMD Vaccine Quality Using ELISA and Lateral Flow Device
3. Keno Strotjohann: Recombination in Vaccine-Derived Polioviruses: Insights from Public Sequencing Data
4. Jasmine Tan: Flavonoid-Based Triflavones as Entry Inhibitors of Enterovirus 71
5. Marine Faucher: Development of Antivirals, Derived From Fluoxetine (Prozac®), Targeting the 2C Protein of Enteroviruses
6. Valeria Lulla: Journal of General Virology

Lecture Session V – Pathogenesis, Prevention, and Treatment
(Chair: Caroline Tapparel Vu)

1. Efrem Alessandro Foglia: Development of a Sandwich ELISA for Rapid Detection of Seneca Valley Virus
2. Stefano Giunta: Targeting Rhinovirus IRES as New Approach for Antivirals
3. Kristina Lanko: Enterovirus A71 Infection in Spinal Motor Neurons: A Chromatin Perspective and Functional Outcomes
4. Raul Andino: Overcoming cVDPVs: Next-Generation Oral Polio Vaccine Design
5. Szarina Ko: Enterovirus Replicons as Self-Amplifying RNA Vaccines
6. Javier Martin: Decoding Poliovirus Transmission and Evolution in the Eradication Endgame